What is the Astragaloside A?

Astragaloside A is white powder, while it's Molecular Formula is C 41 H 68 O 14 . white powder Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine. Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α. Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.

What is the CAS number for Astragaloside A?

The CAS number of Astragaloside A is 83207-58-3.

Product classification

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83207-58-3

Product Name:Astragaloside A
Molecular Formula:C₄₁H₆₈O₁₄
Molecular Weight:784.983
Appearance:white powder

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Product Details

pd_meltingpoint:284-286oC

Appearance:white powder

Purity:99%

Trustworthy Factory Supply Astragaloside A, Factory Sells 83207-58-3 with Lowest Price

Molecular Formula:C₄₁H₆₈O₁₄
Molecular Weight:784.983
Appearance/Colour:white powder
Vapor Pressure:0mmHg at 25°C
Melting Point:284-286oC
Refractive Index:1.62
Boiling Point:895.666 °C at 760 mmHg
PKA:12.91±0.70(Predicted)
Flash Point:495.481 °C
PSA：228.22000
Density:1.395 g/cm³
LogP:0.72410

Astragaloside A(Cas 83207-58-3) Usage

Description	Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases.
Uses	Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine. Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α. Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.
Health effects	As the main active ingredient of the Chinese medicine Astragalus membranaceus, Astragaloside A has a good regulatory effect on the heart. It can protect against ischemic and hypoxic cardiomyocytes, protect the heart structure, and enhance heart function.
Pharmaceutical Applications	Astrageloside A has multiple pharmacologic effects, including anti-inflammatory, antifibrotic, antioxidative stress, anti-asthma, antidiabetes, immunoregulation, and cardioprotective effect via numerous signaling pathways. According to the existing studies and clinical practices, Astragaloside A possesses potential for broad application in many diseases.

InChI:InChI=1/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27?,28-,29+,30?,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

83207-58-3 Relevant articles

TRITERPENE GLYCOSIDES OF Astragalus AND THEIR GENINS. XV. CYCLOSIVERSIOSIDES B AND D FROM Astragalus basineri

Umarova, R. U.,Svechnikova, A. N.,Abdullaev, N. D.,Gorovich, M. B.,Abubakirov, N. K.

, p. 174 - 177 (1984)

Two new glycosides have been isolated fr...

Functional Characterization and Protein Engineering of a Triterpene 3-/6-/2′-O-Glycosyltransferase Reveal a Conserved Residue Critical for the Regiospecificity

Bao, Yang-Oujie,Gao, Bai-Han,Li, Fu-Dong,Qiao, Xue,Shi, Xiao-Meng,Su, Hui-Fei,Wang, Hai-Dong,Ye, Min,Yi, Yang,Zhang, Meng

supporting information, (2022/01/06)

Engineering the function of triterpene g...

Synthetic Access Toward Cycloastragenol Glycosides

Liu, Ting,Liao, Jin-Xi,Hu, Yang,Tu, Yuan-Hong,Sun, Jian-Song

, p. 4170 - 4178 (2017/04/27)

The first efficient synthetic approach t...

Triterpene glycosides from Tragacantha stipulosa and their genins. Structure of cyclostipuloside E

Kaipnazarov,Uteniyazov,Saatov

, p. 40 - 44 (2007/10/03)

The known compound trojanoside A(1) and ...

83207-58-3 Process route

: 3-O-(2,3,4-tri-O-benzoyl-β-D-xylopyranosyl)-6-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-16,25-di-O-acetylcycloastragenol

: 83207-58-3,84687-43-4
astragaloside IV

Conditions

Conditions	Yield
With sodium methylate; In methanol; at 20 ℃; for 15h;	76%

: 84687-45-6
astragaloside VI

: 83207-58-3,84687-43-4
astragaloside IV

Conditions

Conditions	Yield
hesperidinase; In water; acetone; at 35 ℃; for 36h;	35 mg

83207-58-3 Upstream products

88192-83-0
cyclosiversioside H
86764-11-6
isoastragalosides II
84676-88-0
isoastragaloside I
84687-46-7
(3β,6α,16β,20R,24S)-20,24-epoxy-16-hydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostane-6,25-diyl bis[β-D-glucopyranoside]

83207-58-3 Downstream products

84605-18-5
cycloastragenol
86764-12-7
cyclosieversigenin 6-O-β-D-glucopyranoside
86541-79-9
astragenol
86541-83-5
cyclosieversigenin 3-O-β-D-xylopyranoside

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